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Statistics > Machine Learning

Title: EEG machine learning with Higuchi fractal dimension and Sample Entropy as features for successful detection of depression

Abstract: Reliable diagnosis of depressive disorder is essential for both optimal treatment and prevention of fatal outcomes. In this study, we aimed to elucidate the effectiveness of two non-linear measures, Higuchi Fractal Dimension (HFD) and Sample Entropy (SampEn), in detecting depressive disorders when applied on EEG. HFD and SampEn of EEG signals were used as features for seven machine learning algorithms including Multilayer Perceptron, Logistic Regression, Support Vector Machines with the linear and polynomial kernel, Decision Tree, Random Forest, and Naive Bayes classifier, discriminating EEG between healthy control subjects and patients diagnosed with depression. We confirmed earlier observations that both non-linear measures can discriminate EEG signals of patients from healthy control subjects. The results suggest that good classification is possible even with a small number of principal components. Average accuracy among classifiers ranged from 90.24% to 97.56%. Among the two measures, SampEn had better performance. Using HFD and SampEn and a variety of machine learning techniques we can accurately discriminate patients diagnosed with depression vs controls which can serve as a highly sensitive, clinically relevant marker for the diagnosis of depressive disorders.
Comments: 34 pages, 4 Figures, 2 tables
Subjects: Machine Learning (stat.ML); Learning (cs.LG); Neurons and Cognition (q-bio.NC)
Cite as: arXiv:1803.05985 [stat.ML]
  (or arXiv:1803.05985v1 [stat.ML] for this version)

Submission history

From: Milena Čukić Dr [view email]
[v1] Thu, 15 Mar 2018 20:13:38 GMT (747kb)