cicyt UNIZAR
Full-text links:

Download:

Current browse context:

q-bio.PE

Change to browse by:

References & Citations

Bookmark

(what is this?)
CiteULike logo BibSonomy logo Mendeley logo del.icio.us logo Digg logo Reddit logo ScienceWISE logo

Quantitative Biology > Populations and Evolution

Title: The complexity of comparing multiply-labelled trees by extending phylogenetic-tree metrics

Abstract: A multilabeled tree (or MUL-tree) is a rooted tree in which every leaf is labelled by an element from some set, but in which more than one leaf may be labelled by the same element of that set. In phylogenetics, such trees are used in biogeographical studies, to study the evolution of gene families, and also within approaches to construct phylogenetic networks. A multilabelled tree in which no leaf-labels are repeated is called a phylogenetic tree, and one in which every label is the same is also known as a tree-shape. In this paper, we consider the complexity of computing metrics on MUL-trees that are obtained by extending metrics on phylogenetic trees. In particular, by restricting our attention to tree shapes, we show that computing the metric extension on MUL-trees is NP complete for two well-known metrics on phylogenetic trees, namely, the path-difference and Robinson Foulds distances. We also show that the extension of the Robinson Foulds distance is fixed parameter tractable with respect to the distance parameter. The path distance complexity result allows us to also answer an open problem concerning the complexity of solving the quadratic assignment problem for two matrices that are a Robinson similarity and a Robinson dissimilarity, which we show to be NP-complete. We conclude by considering the maximum agreement subtree (MAST) distance on phylogenetic trees to MUL-trees. Although its extension to MUL-trees can be computed in polynomial time, we show that computing its natural generalization to more than two MUL-trees is NP-complete, although fixed-parameter tractable in the maximum degree when the number of given trees is bounded.
Comments: 31 pages, 6 figures
Subjects: Populations and Evolution (q-bio.PE); Data Structures and Algorithms (cs.DS); Combinatorics (math.CO)
Cite as: arXiv:1803.05866 [q-bio.PE]
  (or arXiv:1803.05866v1 [q-bio.PE] for this version)

Submission history

From: Katharina Huber [view email]
[v1] Thu, 15 Mar 2018 17:00:24 GMT (399kb,D)